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An Image-based fluorescence cell analyzer

ADAMII™ LS is a benchtop fluorescent intensity based cell analyzer providing versatile assays and high accurate results (similarity to flow cytometer).

KEY FEATURES & BENEFITS

- Bright field and 3 fluorescence channels (GFP/RFP/DAPI)

- Fluorescence level / Transfection efficiency / Protein expression

- Cell cycle

- Apoptosis

- Total cell counting / Viability / Cell size

- Dot plot

- 21 CFR part 11 compliance for GMP

Technology
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FAQ

ADAMII™ LS,

An image-based fluorescence cell analyzer providing high-quality cell analysis with reliable results

Advantage #1

High-quality cell analysis

ADAMII^TMLS provides high reliability and utilization in cell analysis with multiple frame photographing technique. The slides used for ADAMII^TMLS are available in 1 channel and 2 channel. 1ch slide chamber holds a total of 75 frames, allowing a wide range of measurement for high accuracy.

Advantage #2

Fluorescence analyzer for various samples

- Mammalian cell containing fluorescent protein (GFP, RFP)

- Transfection efficiency

- Cell cycle with PI staining

- Apoptosis

Advantage #3

Fluorescence staining for better performance

- By counting only nucleus cells (Iymphocyte) through fluorescence staining, total cell counting becomes easier and more precise.

- ADAMII^TMLS uses Acridine Orange (AO) and DAPI reagent, which are cell permeable dye and impermeable DNA dye, respectively, for higher accuracy. Thus, it allows user to measure various reagents and cell samples.

Advantage #4

Easy and simple use

ADAMII^TMLS is designed for easy and simple process. It is an user-independent analyzer that does not require any expert to perform. ADAMII^TMLS is a maintenance-free and benchtop-sized instrument for user convenience.

Reference paper of using ADAMII™ LS

	Title
	Development of new TAK-285 derivatives as potent EGFR/HER2 inhibitors possessing antiproliferative effects against 22RV1 and PC3 prostate carcinoma cell lines. Journal of Enzyme Inhibition and Medicinal Chemistry, 2023. Link: https://doi.org/10.1080/14756366.2023.2202358
	Machine Learning-Based Approach to Developing Potent EGFR Inhibitors for Breast Cancer─ Design, Synthesis, and In Vitro Evaluation. ACS omega, 2023 Link: https://doi.org/10.1021/acsomega.3c02799
	Targeting Breast Cancer with Rationally Designed Quinazolines: A Scaffold Hopping Strategy, Journal of Molecular Structure, 2024 Link: https://doi.org/10.1016/j.molstruc.2024.138805
	Optimization of multifunctional NaYbF4:Er3+ upconversion nanoparticle-based dual drug delivery system for enhanced chemo-photodynamic therapy in prostate cancer, Colloids and Surfaces B: Biointerfaces, 2025 Link: https://doi.org/10.1016/j.colsurfb.2025.114919

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FOR RESEARCH USE ONLY.

This product is not approved for diagnostic or therapeutic use.

Objective lens

10 X
Light source

Bright field, UV / Blue / Green LED
Analysis time

App. 2 min–4 min 30 sec (Depends on frames and assay)
Loading volume

25 μL (1ch, 2ch)
Measuring range

5Ⅹ10E4–5Ⅹ10E6 cells/mL

Related downloads Total 3

ADAMII-LS_Brochure_NanoEntek
LS-AN-01-Inducing the polarization of monocyte into macrophages
ADAMII™ LS_Manual

ExTransfection™ Protocol Library

ExTransfection™ provides open protocols that make it easy for users to set up and run experiments. Its 24-well optimization method helps users to optimize transfection protocols easily and quickly.

ExTransfection™ also offers a pre-programmed optimization protocol that helps an easy and quick optimization of electrical parameters for both adherent and suspended cells.

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