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ADAM™ MC

Automated Cell Counter

ADAM™-MC, the automated fluorescence cell counter performs viability and cell counting measurements by using the PI(Propidium Iodide) staining method combined with advanced image analysis.
KEY FEATURES & BENEFITS
- Less than 1 min to get results 
 - Automated image analysis
- Accurate result
- Sensitive CCD detection and precise automatic stage
- Auto focusing



 

A New Standard of Automated Cell counter 
ADAM™-MC, the automated fluorescence cell counter, performs viability and cell counting measurements using the PI(Propidium Iodide) staining method of dead-cell staining combined with advanced image analysis.

- Less than 1 min to get results
- Automated image analysis
- Accurate result
- Sensitive CCD detection and precise automatic stage
- Auto focusing





ADVANTAGE #1

New Standard of Automated Cell Counting

The ADAM™ series automatic cell counter measures total cell numbers and cell viability through cutting-edge detection technologies.
Instead of trypan blue staining which can lead to inaccurate data, ADAM™ utilizes sensitive fluorescence dye staining, LED optics and CCD detection technologies. 
 

ADVANTAGE #2 

Principle of Viability Measurement (PI-Staining Method)

 After the samples are stained with fluorescent dye, propidium iodide, which intercalates DNA to stain the nucleus of target cells, ADAM™-MC takes fluorescent images automatically. The obtained images are processed by image analysis software integrated inside the system

 
   
ADVANTAGE #3 

Disposable Microchips

The ADAM™ series automated cell counter utilizes a precision disposable microchip to eliminate the problem of a permanent counting chamber.
Each microchip is designed for single use. Pumping, cleansing, and wasting slides are not necessary for the ADAM™ cell counter.
Each microchip is produced at our state-of-the-art manufacturing facility and validated for accuracy.



 

ADVANTAGE #3

Accuracy & Reproducibility








ADVANTAGE #4

Comparison with Flow Cytometry


  Comparison of cell viability between ADAM™ and flow cytometry.
SK-OV, HeLa and NCI-H23 cells were treated with 100 and 300 μM of H2O2 for 3 hours, then analyzed by ADAM™ and flow cytometry.
Values are given as mean ± SD of three experiments.










Reference paper of using ADAM™-MC

1. 4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8+ T cell proliferation, Cellular & molecular immunology 14.9 (2017): 748-757.

2. The repopulating cancer cells in melanoma are characterized by increased mitochondrial membrane potential, Cancer letters 382.2 (2016): 188-194

3. Phase I Clinical Trial of 4-1BB-based Adoptive T-cell therapy for Epstein-Barr Virus (EBV)-positive tumors, Journal of Immunotherapy (Hagerstown, Md.: 1997) 39.3 (2016): 140.




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FOR RESEARCH USE ONLY.
This product is not approved for diagnostic or therapeutic use.

  • Product name / Cat. No.

    ADAM–MC / ADAM–MC

  • Loading Volume

    13 μL / test (AccuChip 4ch)

  • Measuring Volume

    3.1 μL / test (AccuChip 4ch)

  • Measure range

    5 x 10E4–4 x 10E6 cell / mL

  • Focus

    Auto focusing

  • LED

    4W Green LED

  • Weight

    9.0 kg

  • Size

    220 (W) x 375 (L) x 250 (H) mm

  • Analysis time

    < 1 min (AccuChip 4ch)

  • Dyes

    PI (Propidium Iodide)

  • Connectivity

    N/A

  • Cell type

    Cell line (clumpy cell, single cell), PBMCs, Adipose Stem cell, Total white blood cell, Primary cells

Related downloads Total 2

  • ADAM-MC_brochure_NanoEntek

    다운로드

  • ADAM-MC_user_manual_NanoEntek

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